Place chuck roast in crockpot. Pour beer over the top of the beef. Sprinkle pepper, salt, garlic powder, onion powder, and chili powder over the top.
Cover and cook on low for 8-10 hours.
An hour or two before you want to eat it, drain all liquid from crockpot and shred the beef.
Stir in the BBQ sauce and brown sugar and cook on low for another hour or two or until heated through.
Serve on buns.